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The Enigma of Rapamycin Dosage

The mammalian target of rapamycin (mTOR) pathway is a critical regulator of cell growth, proliferation, metabolism and survival. Dysregulation of mTOR signaling has been observed in most cancers and thus, the mTOR pathway has been extensively studied for therapeutic intervention. Rapamycin is a natu...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Mukhopadhyay, Suman, Frias, Maria A., Chatterjee, Amrita, Yellen, Paige, Foster, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783198/
https://ncbi.nlm.nih.gov/pubmed/26916116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0720
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