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Developmental inhibition of Gsk3 rescues behavioral and neurophysiological deficits in a mouse model of schizophrenia predisposition

While the genetic basis of schizophrenia is increasingly well-characterized, novel treatments will require establishing mechanistic relationships between specific risk genes and core phenotypes. Rare, highly-penetrant risk genes such as the 22q11.2 microdeletion are promising in this regard. Df(16)A...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Tamura, Makoto, Mukai, Jun, Gordon, Joshua A., Gogos, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783174/
https://ncbi.nlm.nih.gov/pubmed/26898776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.01.025
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