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Cyclin-Dependent Kinase CRK9, Required for Spliced Leader trans Splicing of Pre-mRNA in Trypanosomes, Functions in a Complex with a New L-Type Cyclin and a Kinetoplastid-Specific Protein

In eukaryotes, cyclin-dependent kinases (CDKs) control the cell cycle and critical steps in gene expression. The lethal parasite Trypanosoma brucei, member of the phylogenetic order Kinetoplastida, possesses eleven CDKs which, due to high sequence divergence, were generically termed CDC2-related kin...

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Publicat a:PLoS Pathog
Autors principals: Badjatia, Nitika, Park, Sung Hee, Ambrósio, Daniela L., Kirkham, Justin K., Günzl, Arthur
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783070/
https://ncbi.nlm.nih.gov/pubmed/26954683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005498
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