Trans splicing in trypanosomes requires methylation of the 5' end of the spliced leader RNA.
Trypanosoma brucei spliced leader (SL) RNA contains an unusual cap 4 structure consisting of 7-methylguanosine linked to four modified nucleosides. During RNA maturation, trans splicing transfers the first 39 nucleotides of the SL RNA including the cap structure to the 5' end of all mRNAs. Here we s...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52870/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1719544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.10074 |
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