Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma

Epigenetic therapies such as histone deacetylase inhibitors (HDACi) not only have the capability to decrease tumor cell proliferation and to induce tumor cell death but also to silence antiviral response genes. Here, we investigated whether the combination of an oncolytic measles vaccine virus (MeV)...

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Bibliografiske detaljer
Udgivet i:Mol Ther Oncolytics
Main Authors: Ruf, Benjamin, Berchtold, Susanne, Venturelli, Sascha, Burkard, Markus, Smirnow, Irina, Prenzel, Tanja, Henning, Stefan W, Lauer, Ulrich M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782956/
https://ncbi.nlm.nih.gov/pubmed/27119111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.19
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