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Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma

Epigenetic therapies such as histone deacetylase inhibitors (HDACi) not only have the capability to decrease tumor cell proliferation and to induce tumor cell death but also to silence antiviral response genes. Here, we investigated whether the combination of an oncolytic measles vaccine virus (MeV)...

詳細記述

保存先:
書誌詳細
出版年:Mol Ther Oncolytics
主要な著者: Ruf, Benjamin, Berchtold, Susanne, Venturelli, Sascha, Burkard, Markus, Smirnow, Irina, Prenzel, Tanja, Henning, Stefan W, Lauer, Ulrich M
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782956/
https://ncbi.nlm.nih.gov/pubmed/27119111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.19
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