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Chimeric antigen receptor–engineered T cells as oncolytic virus carriers

The use of engineered T cells in adoptive transfer therapies has shown significant promise in treating hematological cancers. However, successes treating solid tumors are much less prevalent. Oncolytic viruses (OVs) have the capacity to induce specific lysis of tumor cells and indirectly impact tumo...

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Bibliografske podrobnosti
izdano v:Mol Ther Oncolytics
Main Authors: VanSeggelen, Heather, Tantalo, Daniela GM, Afsahi, Arya, Hammill, Joanne A, Bramson, Jonathan L
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782951/
https://ncbi.nlm.nih.gov/pubmed/27119109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.14
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