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Chimeric antigen receptor–engineered T cells as oncolytic virus carriers

The use of engineered T cells in adoptive transfer therapies has shown significant promise in treating hematological cancers. However, successes treating solid tumors are much less prevalent. Oncolytic viruses (OVs) have the capacity to induce specific lysis of tumor cells and indirectly impact tumo...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: VanSeggelen, Heather, Tantalo, Daniela GM, Afsahi, Arya, Hammill, Joanne A, Bramson, Jonathan L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782951/
https://ncbi.nlm.nih.gov/pubmed/27119109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.14
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