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Disulfide Trapping for Modeling and Structure Determination of Receptor:Chemokine Complexes
Despite the recent breakthrough advances in GPCR crystallography, structure determination of protein-protein complexes involving chemokine receptors and their endogenous chemokine ligands remains challenging. Here we describe disulfide trapping, a methodology for generating irreversible covalent bin...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4782801/ https://ncbi.nlm.nih.gov/pubmed/26921956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.12.001 |
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