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RNA-induced conformational changes in a viral coat protein studied by hydrogen/deuterium exchange mass spectrometry

A detailed knowledge of the capsid assembly pathways of viruses from their coat protein building blocks is required to devise novel therapeutic strategies to inhibit such assembly. In the quest for understanding how assembly of single-stranded RNA viruses is achieved at the molecular level, HDX-MS h...

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Bibliografiske detaljer
Udgivet i:Phys Chem Chem Phys
Main Authors: Morton, Victoria L., Burkitt, William, O’Connor, Gavin, Stonehouse, Nicola J., Stockley, Peter G., Ashcroft, Alison E.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782220/
https://ncbi.nlm.nih.gov/pubmed/20877857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cp00817f
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