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A proteomics-based approach identifies secreted protein acidic and rich in cysteine as a prognostic biomarker in malignant pleural mesothelioma

BACKGROUND: We aimed to identify prognostic blood biomarkers using proteomics-based approaches in malignant pleural mesothelioma (MPM). METHODS: Plasma samples from 12 MPM patients were used for exploratory mass spectrometry and ELISA analyses. The significance of secreted protein acidic and rich in...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Kao, Steven C, Kirschner, Michaela B, Cooper, Wendy A, Tran, Thang, Burgers, Sjaak, Wright, Casey, Korse, Tiny, van den Broek, Daan, Edelman, James, Vallely, Michael, McCaughan, Brian, Pavlakis, Nick, Clarke, Stephen, Molloy, Mark P, van Zandwijk, Nico, Reid, Glen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782201/
https://ncbi.nlm.nih.gov/pubmed/26889976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.470
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