Transcriptional suppression of the miR-15/16 family by c-Myc in malignant pleural mesothelioma

MicroRNA downregulation is frequent in malignant pleural mesothelioma (MPM), but the mechanisms responsible for loss of miR-15/16 and miR-193a are yet to be elucidated and were investigated in this study. Copy Number Variation (CNV) of microRNA-coding genes was analyzed in MPM cells by digital dropl...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Williams, Marissa, Cheng, Yuen Yee, Kirschner, Michaela B., Sarun, Kadir H., Schelch, Karin, Winata, Patrick, McCaughan, Brian, Kao, Steven, Van Zandwijk, Nico, Reid, Glen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609241/
https://ncbi.nlm.nih.gov/pubmed/31289611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27010
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