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Predicting Essential Genes and Proteins Based on Machine Learning and Network Topological Features: A Comprehensive Review

Essential proteins/genes are indispensable to the survival or reproduction of an organism, and the deletion of such essential proteins will result in lethality or infertility. The identification of essential genes is very important not only for understanding the minimal requirements for survival of...

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Bibliografske podrobnosti
izdano v:Front Physiol
Main Authors: Zhang, Xue, Acencio, Marcio Luis, Lemke, Ney
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781880/
https://ncbi.nlm.nih.gov/pubmed/27014079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00075
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