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Predicting Essential Genes and Proteins Based on Machine Learning and Network Topological Features: A Comprehensive Review

Essential proteins/genes are indispensable to the survival or reproduction of an organism, and the deletion of such essential proteins will result in lethality or infertility. The identification of essential genes is very important not only for understanding the minimal requirements for survival of...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Zhang, Xue, Acencio, Marcio Luis, Lemke, Ney
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781880/
https://ncbi.nlm.nih.gov/pubmed/27014079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00075
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