NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype

Increasing evidence supports the hypothesis that cancer stem cells (CSCs) are resistant to antiproliferative therapies, able to repopulate tumor bulk, and seed metastasis. NK cells are able to target stem cells as shown by their ability to reject allogeneic hematopoietic stem cells but not solid tis...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Ames, Erik, Canter, Robert J., Grossenbacher, Steven K., Mac, Stephanie, Chen, Mingyi, Smith, Rachel C., Hagino, Takeshi, Perez-Cunningham, Jessica, Sckisel, Gail D., Urayama, Shiro, Monjazeb, Arta M., Fragoso, Ruben C., Sayers, Thomas J., Murphy, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781667/
https://ncbi.nlm.nih.gov/pubmed/26363055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500447
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