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Fluorouracil plasma monitoring: systematic review and economic evaluation of the My5-FU assay for guiding dose adjustment in patients receiving fluorouracil chemotherapy by continuous infusion.

BACKGROUND: 5-Fluorouracil (5-FU) is a chemotherapy used in colorectal, head and neck (H&N) and other cancers. Dose adjustment is based on body surface area (BSA) but wide variations occur. Pharmacokinetic (PK) dosing is suggested to bring plasma levels into the therapeutic range to promote fewe...

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Detalhes bibliográficos
Publicado no:Health Technol Assess
Main Authors: Freeman, Karoline, Connock, Martin, Cummins, Ewen, Gurung, Tara, Taylor-Phillips, Sian, Court, Rachel, Saunders, Mark, Clarke, Aileen, Sutcliffe, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: NIHR Journals Library 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781223/
https://ncbi.nlm.nih.gov/pubmed/26542268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3310/hta19910
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