Is monitoring of plasma 5-fluorouracil levels in metastatic / advanced colorectal cancer clinically effective? A systematic review

BACKGROUND: Pharmacokinetic guided dosing of 5-fluorouracil chemotherapies to bring plasma 5-fluorouracil into a desired therapeutic range may lead to fewer side effects and better patient outcomes. High performance liquid chromatography and a high throughput nanoparticle immunoassay (My5-FU) have b...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Freeman, Karoline, Saunders, Mark P., Uthman, Olalekan A., Taylor-Phillips, Sian, Connock, Martin, Court, Rachel, Gurung, Tara, Sutcliffe, Paul, Clarke, Aileen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960837/
https://ncbi.nlm.nih.gov/pubmed/27456697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2581-x
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