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RNA sequence of astrovirus: distinctive genomic organization and a putative retrovirus-like ribosomal frameshifting signal that directs the viral replicase synthesis.

The genomic RNA of human astrovirus was sequenced and found to contain 6797 nt organized into three open reading frames (1a, 1b, and 2). A potential ribosomal frameshift site identified in the overlap region of open reading frames 1a and 1b consists of a "shifty" heptanucleotide and an RNA stem-loop...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Jiang, B, Monroe, S S, Koonin, E V, Stine, S E, Glass, R I
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248142/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10539
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