The human astrovirus RNA-dependent RNA polymerase coding region is expressed by ribosomal frameshifting.

The genomic RNA of human astrovirus serotype 1 (HAst-1) contains three open reading frames (ORFs), 1a, 1b, and 2. ORF 1b is located downstream of, and overlaps, 1a, and it has been suggested on the basis of sequence analysis that expression of ORF 1b is mediated through -1 ribosomal frameshifting. T...

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Bibliographic Details
Main Authors: Marczinke, B, Bloys, A J, Brown, T D, Willcocks, M M, Carter, M J, Brierley, I
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC236959/
https://ncbi.nlm.nih.gov/pubmed/8057439
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