Sulforaphane Preconditioning Sensitizes Human Colon Cancer Cells towards the Bioreductive Anticancer Prodrug PR-104A

The chemoprotective properties of sulforaphane (SF), derived from cruciferous vegetables, are widely acknowledged to arise from its potent induction of xenobiotic-metabolizing and antioxidant enzymes. However, much less is known about the impact of SF on the efficacy of cancer therapy through the mo...

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Publicat a:PLoS One
Autors principals: Erzinger, Melanie M., Bovet, Cédric, Hecht, Katrin M., Senger, Sabine, Winiker, Pascale, Sobotzki, Nadine, Cristea, Simona, Beerenwinkel, Niko, Shay, Jerry W., Marra, Giancarlo, Wollscheid, Bernd, Sturla, Shana J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780774/
https://ncbi.nlm.nih.gov/pubmed/26950072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150219
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