Sulforaphane Preconditioning Sensitizes Human Colon Cancer Cells towards the Bioreductive Anticancer Prodrug PR-104A.

The chemoprotective properties of sulforaphane (SF), derived from cruciferous vegetables, are widely acknowledged to arise from its potent induction of xenobiotic-metabolizing and antioxidant enzymes. However, much less is known about the impact of SF on the efficacy of cancer therapy through the mo...

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Main Authors: Melanie M Erzinger, Cédric Bovet, Katrin M Hecht, Sabine Senger, Pascale Winiker, Nadine Sobotzki, Simona Cristea, Niko Beerenwinkel, Jerry W Shay, Giancarlo Marra, Bernd Wollscheid, Shana J Sturla
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2016-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4780774?pdf=render
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