Afamelanotide for Erythropoietic Protoporphyria

BACKGROUND: Erythropoietic protoporphyria is a severe photodermatosis that is associated with acute phototoxicity. Patients with this condition have excruciating pain and a markedly reduced quality of life. We evaluated the safety and efficacy of an α-melanocyte–stimulating hormone analogue, afamela...

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Pubblicato in:N Engl J Med
Autori principali: Langendonk, Janneke G., Balwani, Manisha, Anderson, Karl E., Bonkovsky, Herbert L., Anstey, Alexander V., Bissell, D. Montgomery, Bloomer, Joseph, Edwards, Chris, Neumann, Norbert J., Parker, Charles, Phillips, John D., Lim, Henry W., Hamzavi, Iltefat, Deybach, Jean-Charles, Kauppinen, Raili, Rhodes, Lesley E., Frank, Jorge, Murphy, Gillian M., Karstens, Francois P.J., Sijbrands, Eric J.G., de Rooij, Felix W.M., Lebwohl, Mark, Naik, Hetanshi, Goding, Colin R., Wilson, J.H. Paul, Desnick, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780255/
https://ncbi.nlm.nih.gov/pubmed/26132941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1411481
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