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Increasing TRPV4 expression restores flow-induced dilation impaired in mesenteric arteries with aging
The flow-stimulated intracellular Ca(2+) concentration ([Ca(2+)](i)) rise in endothelial cells is an important early event leading to flow-induced blood vessel dilation. Transient receptor potential vanilloid subtype 4 (TRPV4), a Ca(2+)-permeable cation channel, facilitates the flow-stimulated [Ca(2...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4780030/ https://ncbi.nlm.nih.gov/pubmed/26947561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22780 |
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