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Targeting epidermal growth factor receptor for head and neck squamous cell carcinoma: still lost in translation?

The epidermal growth factor receptor (EGFR) is preferentially expressed in head and neck squamous cell carcinoma (HNSCC), and is a promising therapeutic target. Yet other than cetuximab, no agent targeting EGFR has been approved for this disease, and none has shown benefit over the standard of care....

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Chapman, Christopher H., Saba, Nabil F., Yom, Sue S.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779778/
https://ncbi.nlm.nih.gov/pubmed/27004227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2305-5839.2016.01.01
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