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Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells

Mtss1 is located within chromosomal region 8q23-24, which is one of the three most commonly amplified regions in HNSCC. Mtss1 is lost in metastatic cells but confusingly is commonly overexpressed in primary tumors. Here we address possible reasons why Mtss1 is positively selected for in primary tumo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dawson, John C., Timpson, Paul, Kalna, Gabriela, Machesky, Laura M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245856/
https://ncbi.nlm.nih.gov/pubmed/21927027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.376
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