Enhanced cytotoxic CD8 T cell priming using DC expressing HPV-16 E6/E7-p16(INK4) fusion protein with sequenced anti-PD1

The incidence of human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) has increased in recent decades, though HPV prevention vaccines may reduce this rise in the future. HPV related cancers express the viral oncoproteins E6 and E7. The latter inactivates the tumor suppres...

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Vydáno v:J Immunol
Hlavní autoři: Garcia-Bates, Tatiana M., Kim, Eun, Concha-Benavente, Fernando, Trivedi, Sumita, Mailliard, Robbie B., Gambotto, Andrea, Ferris, Robert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779745/
https://ncbi.nlm.nih.gov/pubmed/26851223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502027
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