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Enhanced cytotoxic CD8 T cell priming using DC expressing HPV-16 E6/E7-p16(INK4) fusion protein with sequenced anti-PD1
The incidence of human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) has increased in recent decades, though HPV prevention vaccines may reduce this rise in the future. HPV related cancers express the viral oncoproteins E6 and E7. The latter inactivates the tumor suppres...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4779745/ https://ncbi.nlm.nih.gov/pubmed/26851223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502027 |
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