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Identification of compounds that modulate retinol signaling using a cell-based qHTS assay
In vertebrates, the retinol (vitamin A) signaling pathway (RSP) controls the biosynthesis and catabolism of all-trans retinoic acid (atRA), which regulates transcription of genes essential for embryonic development. Chemicals that interfere with the RSP to cause abnormal intracellular levels of atRA...
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| Vydáno v: | Toxicol In Vitro |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4779714/ https://ncbi.nlm.nih.gov/pubmed/26820057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2016.01.011 |
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