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Differential Antagonism and Tolerance/Cross-Tolerance Among Nicotinic Acetylcholine Receptor Agonists: Scheduled-Controlled Responding and Hypothermia in C57BL/6J Mice

The tobacco dependence pharmacotherapies varenicline and cytisine act as partial α4β2 nAChR agonists. However, the extent to which α4β2 nAChRs mediate their in vivo effects remains unclear. Nicotine, varenicline, cytisine, and epibatidine were studied in male C57BL/6J mice for their effects on rates...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Behav Pharmacol
Hauptverfasser: de Moura, Fernando B., McMahon, Lance R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779712/
https://ncbi.nlm.nih.gov/pubmed/26910582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0000000000000233
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