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Reconstitution and spectroscopic analysis of caveolin-1 residues 62–178 reveals that proline 110 governs its structure and solvent exposure

Caveolin-1 is a membrane protein that possesses an unusual topology where both N- and C- termini are cytoplasmic as a result of a membrane-embedded turn. In particular, proline 110 has been postulated to be the linchpin of this unusual motif. Using a caveolin-1 construct (residues 62–178) reconstitu...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Root, Kyle T., Jebrell Glover, Kerney
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779658/
https://ncbi.nlm.nih.gov/pubmed/26775739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2016.01.007
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