Rare MLL-ELL fusion transcripts in childhood acute myeloid leukemia—association with young age and myeloid sarcomas?

BACKGROUND: The chromosomal translocation t(11;19)(q23;p13) with a breakpoint within subband 19p13.1 is found mainly in acute myeloid leukemia (AML) and results in the MLL-ELL fusion gene. Variations in the structure of MLL-ELL seem to influence the leukemogenic potency of the fusion in vivo and may...

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Sparad:
Bibliografiska uppgifter
I publikationen:Exp Hematol Oncol
Huvudupphovsmän: Panagopoulos, Ioannis, Gorunova, Ludmila, Kerndrup, Gitte, Spetalen, Signe, Tierens, Anne, Osnes, Liv T. N., Andersen, Kristin, Müller, Lil-Sofie Ording, Hellebostad, Marit, Zeller, Bernward, Heim, Sverre
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Case Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779576/
https://ncbi.nlm.nih.gov/pubmed/26949571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-016-0037-2
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