Lineage Reprogramming of Fibroblasts to Proliferative Induced Cardiac Progenitor Cells by Defined Factors

Several studies have reported reprogramming of fibroblasts to induced cardiomyocytes; however, reprogramming to proliferative induced cardiac progenitor cells (iCPCs) remains to be accomplished. Here we report that a combination of eleven or five cardiac factors along with canonical Wnt and JAK/STAT...

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Опубликовано в: :Cell Stem Cell
Главные авторы: Lalit, Pratik A., Salick, Max R., Nelson, Daryl O., Squirrell, Jayne M., Shafer, Christina M., Patel, Neel G., Saeed, Imaan, Schmuck, Eric G., Markandeya, Yogananda S., Wong, Rachel, Lea, Martin R., Eliceiri, Kevin W., Hacker, Timothy, Crone, Wendy C., Kyba, Michael, Garry, Daniel J., Stewart, Ron, Thomson, James A., Downs, Karen M., Lyons, Gary E., Kamp, Timothy J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779406/
https://ncbi.nlm.nih.gov/pubmed/26877223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.12.001
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