Genetic Variation in Toll-Interacting Protein Is Associated With Leprosy Susceptibility and Cutaneous Expression of Interleukin 1 Receptor Antagonist

Leprosy is a chronic disease characterized by skin and peripheral nerve pathology and immune responses that fail to control Mycobacterium leprae. Toll-interacting protein (TOLLIP) regulates Toll-like receptor (TLR) and interleukin 1 receptor (IL-1R) signaling against mycobacteria. We analyzed messen...

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Vydáno v:J Infect Dis
Hlavní autoři: Shah, Javeed A., Berrington, William R., Vary, James C., Wells, Richard D., Peterson, Glenna J., Kunwar, Chhatra B., Khadge, Saraswoti, Hagge, Deanna A., Hawn, Thomas R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779304/
https://ncbi.nlm.nih.gov/pubmed/26610735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv570
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