Human Beta-Defensin 3 Is Up-Regulated in Cutaneous Leprosy Type 1 Reactions

BACKGROUND: Leprosy, a chronic granulomatous disease affecting the skin and nerves, is caused by Mycobacterium leprae (M. leprae). The type of leprosy developed depends upon the host immune response. Type 1 reactions (T1Rs), that complicate borderline and lepromatous leprosy, are due to an increase...

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Hlavní autoři: Cogen, Anna L., Walker, Stephen L., Roberts, Chrissy H., Hagge, Deanna A., Neupane, Kapil D., Khadge, Saraswoti, Lockwood, Diana N. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486878/
https://ncbi.nlm.nih.gov/pubmed/23133681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001869
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