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Production and fluorescence-activated cell sorting of Escherichia coli expressing a functional antibody fragment on the external surface.

We have expressed a single chain Fv (scFv) antibody fragment, consisting of the variable heavy and variable light domains from two separate anti-digoxin monoclonal antibodies, on the external surface of Escherichia coli by fusing it to an Lpp-OmpA hybrid previously shown to direct heterologous prote...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Francisco, J A, Campbell, R, Iverson, B L, Georgiou, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC47793/
https://ncbi.nlm.nih.gov/pubmed/8248129
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