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Initial Characterization of Integrase-Defective Lentiviral Vectors for Pancreatic Cancer Gene Therapy

The vast majority (85%) of pancreatic ductal adenocarcinomas (PDACs) are discovered at too of a late stage to allow curative surgery. In addition, PDAC is highly resistant to conventional methods of chemotherapy and radiotherapy, which only offer a marginal clinical benefit. Consequently, the progno...

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Detalles Bibliográficos
Publicado en:Hum Gene Ther
Autores principales: Hanoun, Naima, Gayral, Marion, Pointreau, Adeline, Buscail, Louis, Cordelier, Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779299/
https://ncbi.nlm.nih.gov/pubmed/26731312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2015.151
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