A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle

BACKGROUND: The understanding of changes in temporal processes related to human carcinogenesis is limited. One approach for prospective functional genomic studies is to compile trajectories of differential expression of genes, based on measurements from many case-control pairs. We propose a new stat...

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Pubblicato in:BMC Med Res Methodol
Autori principali: Lund, Eiliv, Holden, Lars, Bøvelstad, Hege, Plancade, Sandra, Mode, Nicolle, Günther, Clara-Cecilie, Nuel, Gregory, Thalabard, Jean-Christophe, Holden, Marit
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779232/
https://ncbi.nlm.nih.gov/pubmed/26944545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-016-0129-z
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