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A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle

BACKGROUND: The understanding of changes in temporal processes related to human carcinogenesis is limited. One approach for prospective functional genomic studies is to compile trajectories of differential expression of genes, based on measurements from many case-control pairs. We propose a new stat...

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Bibliographic Details
Published in:BMC Med Res Methodol
Main Authors: Lund, Eiliv, Holden, Lars, Bøvelstad, Hege, Plancade, Sandra, Mode, Nicolle, Günther, Clara-Cecilie, Nuel, Gregory, Thalabard, Jean-Christophe, Holden, Marit
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779232/
https://ncbi.nlm.nih.gov/pubmed/26944545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-016-0129-z
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