Intranasal Delivery of Exendin-4 Confers Neuroprotective Effect Against Cerebral Ischemia in Mice

Exendin-4 is now considered as a promising drug for the treatment of cerebral ischemia. To determine the neuroprotective effects of intranasal exendin-4, C57BL/6J mice were intranasally administered with exendin-4 daily for 7 days before middle cerebral artery occlusion (MCAO) surgery. Intranasally...

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Bibliographic Details
Published in:AAPS J
Main Authors: Zhang, Huinan, Meng, Jingru, Zhou, Shimeng, Liu, Yunhan, Qu, Di, Wang, Ling, Li, Xubo, Wang, Ning, Luo, Xiaoxing, Ma, Xue
Format: Artigo
Language:Inglês
Published: Springer US 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779090/
https://ncbi.nlm.nih.gov/pubmed/26689204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9854-1
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