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Intranasal Delivery of Exendin-4 Confers Neuroprotective Effect Against Cerebral Ischemia in Mice
Exendin-4 is now considered as a promising drug for the treatment of cerebral ischemia. To determine the neuroprotective effects of intranasal exendin-4, C57BL/6J mice were intranasally administered with exendin-4 daily for 7 days before middle cerebral artery occlusion (MCAO) surgery. Intranasally...
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Published in: | AAPS J |
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Main Authors: | , , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
Springer US
2015
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4779090/ https://ncbi.nlm.nih.gov/pubmed/26689204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9854-1 |
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