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Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels
Pentameric ligand-gated ion channels are activated by the binding of agonists to a site distant from the ion conduction path. These membrane proteins consist of distinct ligand-binding and pore domains that interact via an extended interface. Here, we have investigated the role of residues at this i...
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| Publicado no: | PLoS Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778918/ https://ncbi.nlm.nih.gov/pubmed/26943937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002393 |
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