The Myeloid LSECtin Is a DAP12-Coupled Receptor That Is Crucial for Inflammatory Response Induced by Ebola Virus Glycoprotein

Fatal Ebola virus infection is characterized by a systemic inflammatory response similar to septic shock. Ebola glycoprotein (GP) is involved in this process through activating dendritic cells (DCs) and macrophages. However, the mechanism is unclear. Here, we showed that LSECtin (also known as CLEC4...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Zhao, Dianyuan, Han, Xintao, Zheng, Xuexing, Wang, Hualei, Yang, Zaopeng, Liu, Di, Han, Ke, Liu, Jing, Wang, Xiaowen, Yang, Wenting, Dong, Qingyang, Yang, Songtao, Xia, Xianzhu, Tang, Li, He, Fuchu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778874/
https://ncbi.nlm.nih.gov/pubmed/26943817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005487
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