The Myeloid LSECtin Is a DAP12-Coupled Receptor That Is Crucial for Inflammatory Response Induced by Ebola Virus Glycoprotein

Fatal Ebola virus infection is characterized by a systemic inflammatory response similar to septic shock. Ebola glycoprotein (GP) is involved in this process through activating dendritic cells (DCs) and macrophages. However, the mechanism is unclear. Here, we showed that LSECtin (also known as CLEC4...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Zhao, Dianyuan, Han, Xintao, Zheng, Xuexing, Wang, Hualei, Yang, Zaopeng, Liu, Di, Han, Ke, Liu, Jing, Wang, Xiaowen, Yang, Wenting, Dong, Qingyang, Yang, Songtao, Xia, Xianzhu, Tang, Li, He, Fuchu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778874/
https://ncbi.nlm.nih.gov/pubmed/26943817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005487
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