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Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer

Prostate cancer (PCa) is the second most common cancer in men. The Androgen Receptor (AR) is the major driver of PCa and the main target of therapy in the advanced setting. AR is a nuclear receptor that binds the chromatin and regulates transcription of genes involved in cancer cell proliferation an...

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Publicat a:Genom Data
Autors principals: Nevedomskaya, Ekaterina, Stelloo, Suzan, van der Poel, Henk G., de Jong, Jeroen, Wessels, Lodewyk F.A., Bergman, Andries M., Zwart, Wilbert
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778643/
https://ncbi.nlm.nih.gov/pubmed/26981385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gdata.2015.12.020
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