Increased caveolin-1 in intervertebral disc degeneration facilitates repair

BACKGROUND: Preceding intervertebral disc (IVD) degeneration, the cell phenotype in the nucleus pulposus (NP) shifts from notochordal cells (NCs) to chondrocyte-like cells (CLCs). Microarray analysis showed a correlation between caveolin-1 expression and the phenotypic transition of NCs to CLCs. Wit...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Bach, Frances C., Zhang, Ying, Miranda-Bedate, Alberto, Verdonschot, Lucy C., Bergknut, Niklas, Creemers, Laura B., Ito, Keita, Sakai, Daisuke, Chan, Danny, Meij, Björn P., Tryfonidou, Marianna A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778307/
https://ncbi.nlm.nih.gov/pubmed/26939667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-0960-y
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