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A physiologically-based flow network model for hepatic drug elimination III: 2D/3D DLA lobule models
BACKGROUND: One of the major issues in current pharmaceutical development is potential hepatotoxicity and drug-induced liver damage. This is due to the unique metabolic processes performed in the liver to prevent accumulation of a wide range of chemicals in the blood. Recently, we developed a physio...
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| Publicado no: | Theor Biol Med Model |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778290/ https://ncbi.nlm.nih.gov/pubmed/26939615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12976-016-0034-5 |
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