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Spatiotemporal dynamics of distributed synthetic genetic circuits

We propose and study models of two distributed synthetic gene circuits, toggle-switch and oscillator, each split between two cell strains and coupled via quorum-sensing signals. The distributed toggle switch relies on mutual repression of the two strains, and oscillator is comprised of two strains,...

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Detalles Bibliográficos
Publicado en:Physica D
Main Authors: Kanakov, Oleg, Laptyeva, Tetyana, Tsimring, Lev, Ivanchenko, Mikhail
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778264/
https://ncbi.nlm.nih.gov/pubmed/26955203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physd.2015.10.016
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