GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons

Regulation of AMPA receptor (AMPAR)-mediated synaptic transmission is a key mechanism for synaptic plasticity. In the brain, AMPARs assemble with a number of auxiliary subunits, including TARPs, CNIHs and CKAMP44, which are important for AMPAR forward trafficking to synapses. Here we report that the...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Gu, Xinglong, Mao, Xia, Lussier, Marc P., Hutchison, Mary Anne, Zhou, Liang, Hamra, F. Kent, Roche, Katherine W., Lu, Wei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778064/
https://ncbi.nlm.nih.gov/pubmed/26932439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10873
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items