Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure

The epigenetic information encoded in the genomic DNA methylation pattern is translated by methylcytosine binding proteins like MeCP2 into chromatin topology and structure and gene activity states. We have shown previously that the MeCP2 level increases during differentiation and that it causes larg...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Becker, Annette, Zhang, Peng, Allmann, Lena, Meilinger, Daniela, Bertulat, Bianca, Eck, Daniel, Hofstaetter, Maria, Bartolomei, Giody, Hottiger, Michael O., Schreiber, Valérie, Leonhardt, Heinrich, Cardoso, M. Cristina
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777825/
https://ncbi.nlm.nih.gov/pubmed/26772194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.698357
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