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Cannabinoid control of learning and memory through HCN channels

The mechanisms underlying the effects of cannabinoids on cognitive processes are not understood. Here we show that cannabinoid type-1 receptors (CB1Rs) control hippocampal synaptic plasticity and spatial memory through the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels that under...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Maroso, Mattia, Szabo, Gergely G., Kim, Hannah K., Alexander, Allyson, Bui, Anh D., Lee, Sang-Hun, Lutz, Beat, Soltesz, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777634/
https://ncbi.nlm.nih.gov/pubmed/26898775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.01.023
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