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Genetic Correlations Greatly Increase Mutational Robustness and Can Both Reduce and Enhance Evolvability

Mutational neighbourhoods in genotype-phenotype (GP) maps are widely believed to be more likely to share characteristics than expected from random chance. Such genetic correlations should strongly influence evolutionary dynamics. We explore and quantify these intuitions by comparing three GP maps—a...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Greenbury, Sam F., Schaper, Steffen, Ahnert, Sebastian E., Louis, Ard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777517/
https://ncbi.nlm.nih.gov/pubmed/26937652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004773
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